| Reference |
|---|
| Reference Type | Submission | IEDB_Reference:1014017 |
| Title | Large scale analysis of peptide-HLA class I interactions | |
| Authors | Mikkel Harndahl; Kasper Lamberth; Gustav Roder; Sune Justesen; Michael Madsen; Morten Nielsen; Claus Lundegaard; Mette Voldby Larsen; Sheila Tang; Soren Brunak; Ole Lund; Soren Buus | |
| Affiliations | Div of Experimental Immunology, Dep Med Microbiol Immunol, University of Copenhagen, Cntr Biol Seq Anal, Technical University of Denmark. | |
| Submitter | Soren Buus | IEDB_Submission:1000422 |
| Year | 2009 | |
| Abstract | In general, this data has been generated using a quantitative biochemical peptide-HLA interaction assay (see PMID: 12135423). The HLA class I molecules have been selected to cover the known HLA supertypes (using PMID: 14963618). Predictions of peptide binding to HLA class I has been performed using various bioinformatics approaches including artificial neural networks (see PMID: 14617044 and PMID: 12717023 peptides and using a combined algorithm integrating MHC class I binding, TAP transport efficiency, and proteasomal cleavage predictions (PMID: 15997466). In many cases, the most informative peptides have been selected using a Query-by-Committeee procedure (using PMID: 14617044 and PMID: 14629874). | |
| Curation Last Updated | 2024-11-01 19:45:06 | |