EPITOPE SUMMARY
KVPRNQDWL is a linear peptidic epitope (epitope ID
96518
) studied as part of Melanocyte protein PMEL (UniProt:P40967) from Homo sapiens (human) and Premelanosome protein (Fragment) (UniProt:F8VXH8) from Homo sapiens (human). This epitope has been studied for immune reactivity in
22
publication(s), tested in
64
T cell assays,
4
MHC ligand assays and has 3D structure(s)
3CC5
.
CURATED EXPERIMENTAL DATA
MHC Ligand Assay(s)
4
MHC moleculePositive / All
H2-Db
3
/
3
H2-Kb
0
/
1
T Cell Assay(s)
64
Assay TypePositive / All
IFNg release
17
/
18
qualitative binding
10
/
11
tumor burden after challenge after adoptive transfer
5
/
5
IL-2 release
4
/
4
activation
3
/
3
cytotoxicity
3
/
3
proliferation after adoptive transfer
3
/
3
survival after tumor challenge after adoptive transfer
3
/
3
granzyme B release
2
/
2
proliferation
2
/
2
protection from tumor challenge
2
/
2
TNFa release
2
/
2
cytotoxicity after adoptive transfer
1
/
1
degranulation
1
/
1
IL-6 release
1
/
1
survival from tumor challenge
1
/
1
tumor burden after challenge
1
/
1
decreased disease
0
/
1
EXTERNAL RESOURCES
ResourceLink
IEDB-AR: MHC-I Processing
Predict MHC class I processing
IEDB-AR: MHC-I
Predict MHC class I binding affinity
IEDB-AR: B cell scales
Predict B cell epitopes