3-{beta-D-GlcNAc-(1->3)-[D-GrO-(2->1)]-beta-D-GlcNAc-(6-P-6)-beta-D-GlcNAc-(1->3)-[D-GrO-(2->1)]-beta-D-GlcNAc-(6-P-6)-beta-D-GlcNAc-(1->3)-[D-GrO-(2->1)]-beta-D-GlcNAc-(6-P-6)-beta-D-Glc-(1->6)-beta-D-Glc-(1->6)-beta-D-Glc-yl}-1,2-dimyristoyl-sn-glycerol epitope

EPITOPE SUMMARY
3-{beta-D-GlcNAc-(1->3)-[D-GrO-(2->1)]-beta-D-GlcNAc-(6-P-6)-beta-D-GlcNAc-(1->3)-[D-GrO-(2->1)]-beta-D-GlcNAc-(6-P-6)-beta-D-GlcNAc-(1->3)-[D-GrO-(2->1)]-beta-D-GlcNAc-(6-P-6)-beta-D-Glc-(1->6)-beta-D-Glc-(1->6)-beta-D-Glc-yl}-1,2-dimyristoyl-sn-glycerol (epitope ID 1075901 ) has this structure: CHEBI:150019 studied as part of lipoteichoic acid. The epitope has these synonyms: 3-{2-acetamido-2-deoxy-beta-D-glucopyranosyl-(1->3)-[(1S)-1-carboxy-2-hydroxyethyl-(1->1)]-2-acetamido-2-deoxy-beta-D-glucopyranosyl-(6-phospho-6)-2-acetamido-2-deoxy-beta-D-glucopyranosyl-(1->3)-[(1S)-1-carboxy-2-hydroxyethyl-(1->1)]-2-acetamido-2-deoxy-beta-D-glucopyranosyl-(6-phospho-6)-2-acetamido-2-deoxy-beta-D-glucopyranosyl-(1->3)-[(1S)-1-carboxy-2-hydroxyethyl-(1->1)]-2-acetamido-2-deoxy-beta-D-glucopyranosyl-(6-phospho-6)-2-acetamido-2-deoxy-beta-D-glucopyranosyl-(1->6)-beta-D-glucopyranosyl-(1->6)-beta-D-glucopyranosyl}-1,2-bis(tetradecanoyloxy)-sn-glycerol, (2R)-2-{[(2R,3R,4R,5S,6R)-3-acetamido-4-{[(2S,3R,4R,5S,6R)-3-acetamido-6-({[({(2R,3S,4R,5R,6R)-5-acetamido-4-{[(2S,3R,4R,5S,6R)-3-acetamido-6-({[({(2R,3S,4R,5R,6R)-5-acetamido-4-{[(2S,3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}-6-[(1R)-1-carboxy-2-hydroxyethoxy]-3-hydroxytetrahydro-2H-pyran-2-yl}methoxy)(hydroxy)phosphoryl]oxy}methyl)-4,5-dihydroxytetrahydro-2H-pyran-2-yl]oxy}-6-[(1R)-1-carboxy-2-hydroxyethoxy]-3-hydroxytetrahydro-2H-pyran-2-yl}methoxy)(hydroxy)phosphoryl]oxy}methyl)-4,5-dihydroxytetrahydro-2H-pyran-2-yl]oxy}-6-({[{[(2R,3S,4S,5R,6R)-6-{[(2R,3S,4S,5R,6R)-6-({(2R,3S,4S,5R,6R)-6-[(2S)-2,3-bis(tetradecanoyloxy)propoxy]-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl}methoxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl]methoxy}-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl]methoxy}(hydroxy)phosphoryl]oxy}methyl)-5-hydroxytetrahydro-2H-pyran-2-yl]oxy}-3-hydroxypropanoic acid, 3-{beta-D-GlcpNAc-(1->3)-[D-GrO-(2->1)]-beta-D-GlcpNAc-(6-P-6)-beta-D-GlcpNAc-(1->3)-[D-GrO-(2->1)]-beta-D-GlcpNAc-(6-P-6)-beta-D-GlcpNAc-(1->3)-[D-GrO-(2->1)]-beta-D-GlcpNAc-(6-P-6)-beta-D-Glcp-(1->6)-beta-D-Glcp-(1->6)-beta-D-Glcp-yl}-1,2-dimyristoyl-sn-glycerol, WH237. This epitope has been studied for immune reactivity in 1 publication(s), tested in 15 B cell assays.

EPITOPE SUMMARY

3-{beta-D-GlcNAc-(1->3)-[D-GrO-(2->1)]-beta-D-GlcNAc-(6-P-6)-beta-D-GlcNAc-(1->3)-[D-GrO-(2->1)]-beta-D-GlcNAc-(6-P-6)-beta-D-GlcNAc-(1->3)-[D-GrO-(2->1)]-beta-D-GlcNAc-(6-P-6)-beta-D-Glc-(1->6)-beta-D-Glc-(1->6)-beta-D-Glc-yl}-1,2-dimyristoyl-sn-glycerol (epitope ID

1075901

) has this structure:

CHEBI:150019

studied as part of lipoteichoic acid. The epitope has these synonyms: 3-{2-acetamido-2-deoxy-beta-D-glucopyranosyl-(1->3)-[(1S)-1-carboxy-2-hydroxyethyl-(1->1)]-2-acetamido-2-deoxy-beta-D-glucopyranosyl-(6-phospho-6)-2-acetamido-2-deoxy-beta-D-glucopyranosyl-(1->3)-[(1S)-1-carboxy-2-hydroxyethyl-(1->1)]-2-acetamido-2-deoxy-beta-D-glucopyranosyl-(6-phospho-6)-2-acetamido-2-deoxy-beta-D-glucopyranosyl-(1->3)-[(1S)-1-carboxy-2-hydroxyethyl-(1->1)]-2-acetamido-2-deoxy-beta-D-glucopyranosyl-(6-phospho-6)-2-acetamido-2-deoxy-beta-D-glucopyranosyl-(1->6)-beta-D-glucopyranosyl-(1->6)-beta-D-glucopyranosyl}-1,2-bis(tetradecanoyloxy)-sn-glycerol, (2R)-2-{[(2R,3R,4R,5S,6R)-3-acetamido-4-{[(2S,3R,4R,5S,6R)-3-acetamido-6-({[({(2R,3S,4R,5R,6R)-5-acetamido-4-{[(2S,3R,4R,5S,6R)-3-acetamido-6-({[({(2R,3S,4R,5R,6R)-5-acetamido-4-{[(2S,3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}-6-[(1R)-1-carboxy-2-hydroxyethoxy]-3-hydroxytetrahydro-2H-pyran-2-yl}methoxy)(hydroxy)phosphoryl]oxy}methyl)-4,5-dihydroxytetrahydro-2H-pyran-2-yl]oxy}-6-[(1R)-1-carboxy-2-hydroxyethoxy]-3-hydroxytetrahydro-2H-pyran-2-yl}methoxy)(hydroxy)phosphoryl]oxy}methyl)-4,5-dihydroxytetrahydro-2H-pyran-2-yl]oxy}-6-({[{[(2R,3S,4S,5R,6R)-6-{[(2R,3S,4S,5R,6R)-6-({(2R,3S,4S,5R,6R)-6-[(2S)-2,3-bis(tetradecanoyloxy)propoxy]-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl}methoxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl]methoxy}-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl]methoxy}(hydroxy)phosphoryl]oxy}methyl)-5-hydroxytetrahydro-2H-pyran-2-yl]oxy}-3-hydroxypropanoic acid, 3-{beta-D-GlcpNAc-(1->3)-[D-GrO-(2->1)]-beta-D-GlcpNAc-(6-P-6)-beta-D-GlcpNAc-(1->3)-[D-GrO-(2->1)]-beta-D-GlcpNAc-(6-P-6)-beta-D-GlcpNAc-(1->3)-[D-GrO-(2->1)]-beta-D-GlcpNAc-(6-P-6)-beta-D-Glcp-(1->6)-beta-D-Glcp-(1->6)-beta-D-Glcp-yl}-1,2-dimyristoyl-sn-glycerol, WH237. This epitope has been studied for immune reactivity in

publication(s), tested in

B cell assays.

CURATED EXPERIMENTAL DATA
B Cell Assay(s) 15
Assay Type	Positive / All
qualitative binding	12 / 12
dissociation constant KD	2 / 2
antibody activity inhibition	1 / 1

EXTERNAL RESOURCES
Resource	Link
PubChem	146170790