EPITOPE SUMMARY
benzylpenicillin (epitope ID
114070
) has this structure:
CHEBI:18208
. The epitope has these synonyms: 2,2-dimethyl-6beta-(phenylacetamido)penam-3alpha-carboxylic acid, (2S,5R,6R)-3,3-dimethyl-7-oxo-6-(phenylacetamido)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-(2-phenylacetamido)penicillanic acid, bencilpenicilina, bensylpenicillin, benzyl benicillin, Benzylpenicillin, benzylpenicillin, benzylpenicilline, benzylpenicillinic acid, benzylpenicillinum, free penicillin II, PCG, Penicillin G, PENICILLIN G, PG. This epitope has been studied for immune reactivity in
51
publication(s), tested in
39
T cell assays and
166
B cell assays.
CURATED EXPERIMENTAL DATA
B Cell Assay(s)
166
Assay TypePositive / All
qualitative binding
74
/
82
hypersensitivity
26
/
33
agglutination
17
/
19
histamine release
8
/
9
antibody binding
4
/
7
hypersensitivity after adoptive transfer
4
/
5
hemagglutination inhibition
2
/
4
dissociation constant KD
3
/
3
association constant KA
1
/
1
off rate
1
/
1
on rate
1
/
1
decreased disease
0
/
1
T Cell Assay(s)
39
Assay TypePositive / All
proliferation
23
/
26
IFNg release
5
/
6
IL-4 release
3
/
3
type IV hypersensitivity (DTH)
2
/
2
granzyme B release
1
/
1
IL-2 release
1
/
1
EXTERNAL RESOURCES
ResourceLink
PubChem
5904