EPITOPE SUMMARY
amoxicillin (epitope ID
114241
) has this structure:
CHEBI:2676
. The epitope has these synonyms: 6beta-[(2R)-2-amino-2-(4-hydroxyphenyl)acetamido]-2,2-dimethylpenam-3alpha-carboxylic acid, (2S,5R,6R)-6-{[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-(p-hydroxy-alpha-aminophenylacetamido)penicillanic acid, alpha-amino-p-hydroxybenzylpenicillin, Amolin, Amopenixin, amoxicilina, amoxicillin, Amoxicillin, Amoxicillin anhydrous, amoxicilline, amoxicillinum, amoxycilin, amoxycillin, AMPC, AX, Clamoxyl, Moxal, p-hydroxyampicillin. This epitope has been studied for immune reactivity in
27
publication(s), tested in
23
T cell assays and
108
B cell assays.
CURATED EXPERIMENTAL DATA
B Cell Assay(s)
108
Assay TypePositive / All
qualitative binding
39
/
55
hypersensitivity
20
/
26
dissociation constant KD
6
/
13
histamine release
8
/
10
tolerance
3
/
4
T Cell Assay(s)
23
Assay TypePositive / All
proliferation
16
/
16
activation
1
/
1
granzyme B release
1
/
1
IFNg release
1
/
1
IL-13 release
1
/
1
IL-22 release
1
/
1
perforin release
1
/
1
type IV hypersensitivity (DTH)
1
/
1
EXTERNAL RESOURCES
ResourceLink
PubChem
33613