EPITOPE SUMMARY
alpha-D-galactosyl-(1->3)-D-galactose (epitope ID
115013
) has this structure:
CHEBI:53651
studied as part of Laminin subunit alpha-1 (UniProt:P19137) from Mus musculus (mouse) and alpha-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-D-Glc. The epitope has these synonyms: alpha-D-galactopyranosyl-(1->3)-D-galactose, (Gal)2, 3-O-alpha-D-galactopyranosyl-D-galactopyranose, 3-O-alpha-D-Galactopyranosyl-D-galactose, alpha-D-Gal-(1->3)-D-Gal, alpha-D-galactosyl-(1->3)-D-galactose, alpha-D-Galp-(1->3)-D-Galp, alpha-Gal, alpha1,3Gal, Bdi, Bdi-epitope, dialphaGal, Gal(alpha1-3)Gal, Gal-alpha(1,3)Gal, Gal-alpha1,3-Gal, galactose-alpha-(1,3)-galactose, galactose-alpha-1,3-galactose, Galalpha,3Gal, Galalpha1,3Gal, Galalpha1-3Gal, human blood group type B linear epitope, WURCS=2.0/2,2,1/[a2112h-1x_1-5][a2112h-1a_1-5]/1-2/a3-b1, alpha-gal. This epitope has been studied for immune reactivity in
66
publication(s), tested in
267
B cell assays and has 3D structure(s)
7UEM
and
7UEN
.
CURATED EXPERIMENTAL DATA
B Cell Assay(s)
267
Assay TypePositive / All
qualitative binding
192
/
202
dissociation constant KD
26
/
26
complement-dependent cytotoxicity
12
/
13
hypersensitivity
6
/
6
association constant KA
3
/
5
disease exacerbation after adoptive transfer
3
/
3
tolerance
3
/
3
3D structure
2
/
2
off rate
2
/
2
on rate
2
/
2
antibody activity inhibition
1
/
1
antibody binding
1
/
1
antibody-dependent cellular cytotoxicity
1
/
1
EXTERNAL RESOURCES
ResourceLink
PubChem
16219440
GlyTouCan
G78260AJ