EPITOPE SUMMARY | |
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ELAGIGILTV is a linear peptidic epitope (epitope ID ) studied as part of Protein OPG074 (UniProt:Q80HX1) from Vaccinia virus (vaccinia virus VV). The epitope is an analog of: EAAGIGILTV from Homo sapiens (human) Melanoma antigen recognized by T-cells 1. The epitope is an analog of: EAAGIGILTV from Homo sapiens (human) melanoma antigen recognized by T-cells 1. The epitope is an analog of: AAGIGILTV from Homo sapiens (human) Melanoma antigen recognized by T-cells 1. This epitope has been studied for immune reactivity in publication(s), tested in T cell assays, B cell assays, MHC ligand assays and has 3D structure(s) , , , , , , , , , and . |
CURATED EXPERIMENTAL DATA | |
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MHC Ligand Assay(s) | |
MHC molecule | Positive / All |
HLA-A*02:01 | / |
HLA-A2 | / |
HLA-B*07:02 | / |
B Cell Assay(s) | |
Assay Type | Positive / All |
dissociation constant KD | / |
off rate | / |
on rate | / |
qualitative binding | / |
3D structure | / |
antibody-dependent cellular cytotoxicity | / |
T Cell Assay(s) | |
Assay Type | Positive / All |
qualitative binding | / |
IFNg release | / |
dissociation constant KD | / |
cytotoxicity | / |
TNFa release | / |
proliferation | / |
IL-2 release | / |
off rate | / |
activation | / |
on rate | / |
degranulation | / |
3D structure | / |
T cell- APC binding | / |
CCL4/MIP-1b release | / |
granzyme B release | / |
IL-8 release | / |
perforin release | / |
IL-4 release | / |
IL-10 release | / |
decreased disease | / |
decreased disease after adoptive transfer | / |
IL-17 release | / |
proliferation after adoptive transfer | / |
protection from tumor challenge after adoptive transfer | / |
tumor burden after challenge after adoptive transfer | / |
IL-13 release | / |
IL-5 release | / |
tumor burden after challenge | / |
EXTERNAL RESOURCES | |
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Resource | Link |