EPITOPE SUMMARY
ELAGIGILTV is a linear peptidic epitope (epitope ID ) studied as part of Protein OPG074 (UniProt:Q80HX1) from Vaccinia virus (vaccinia virus VV). The epitope is an analog of: EAAGIGILTV from Homo sapiens (human) Melanoma antigen recognized by T-cells 1. The epitope is an analog of: EAAGIGILTV from Homo sapiens (human) melanoma antigen recognized by T-cells 1. The epitope is an analog of: AAGIGILTV from Homo sapiens (human) Melanoma antigen recognized by T-cells 1. This epitope has been studied for immune reactivity in publication(s), tested in T cell assays, B cell assays, MHC ligand assays and has 3D structure(s) , , , , , , , , , and .
CURATED EXPERIMENTAL DATA
MHC Ligand Assay(s)
MHC moleculePositive / All
HLA-A*02:01
HLA-A2
HLA-B*07:02
B Cell Assay(s)
Assay TypePositive / All
dissociation constant KD
off rate
on rate
qualitative binding
3D structure
antibody-dependent cellular cytotoxicity
T Cell Assay(s)
Assay TypePositive / All
qualitative binding
IFNg release
dissociation constant KD
cytotoxicity
TNFa release
proliferation
IL-2 release
off rate
activation
on rate
degranulation
3D structure
T cell- APC binding
CCL4/MIP-1b release
granzyme B release
IL-8 release
perforin release
IL-4 release
IL-10 release
decreased disease
decreased disease after adoptive transfer
IL-17 release
proliferation after adoptive transfer
protection from tumor challenge after adoptive transfer
tumor burden after challenge after adoptive transfer
IL-13 release
IL-5 release
tumor burden after challenge
EXTERNAL RESOURCES
ResourceLink