abacavir epitope - Immune Epitope Database (IEDB)

EPITOPE SUMMARY
abacavir (epitope ID 137341 ) has this structure: CHEBI:421707 . The epitope has these synonyms: {(1S,4R)-4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]cyclopent-2-en-1-yl}methanol, Abacavir, abacavir, ABC, {(1S-cis)-4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]cyclopent-2-en-1-yl}methanol. This epitope has been studied for immune reactivity in 15 publication(s), tested in 56 T cell assays, 7 MHC ligand assays and has 3D structure(s) 5U98 , 3VRI , 3VRJ and 3UPR .

EPITOPE SUMMARY

abacavir (epitope ID

) has this structure:

. The epitope has these synonyms: {(1S,4R)-4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]cyclopent-2-en-1-yl}methanol, Abacavir, abacavir, ABC, {(1S-cis)-4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]cyclopent-2-en-1-yl}methanol. This epitope has been studied for immune reactivity in

publication(s), tested in

T cell assays,

MHC ligand assays and has 3D structure(s)

and

CURATED EXPERIMENTAL DATA
MHC Ligand Assay(s) 7
MHC molecule	Positive / All
HLA-B*57:01	7 / 7

T Cell Assay(s) 56
Assay Type	Positive / All
IFNg release	27 / 32
activation	4 / 4
cytotoxicity	3 / 3
proliferation	3 / 3
TNFa release	3 / 3
degranulation	2 / 2
type IV hypersensitivity (DTH)	2 / 2
granzyme B release	1 / 1
IL-10 release	1 / 1
IL-13 release	1 / 1
IL-2 release	1 / 1
IL-5 release	1 / 1
perforin release	1 / 1
qualitative binding	1 / 1

EXTERNAL RESOURCES
Resource	Link
PubChem	441300