1-O-(alpha-D-galactopyranosyl)-N-icosa-11,14-dienoylphytosphingosine epitope

EPITOPE SUMMARY
1-O-(alpha-D-galactopyranosyl)-N-icosa-11,14-dienoylphytosphingosine (epitope ID 158634 ) has this structure: CHEBI:60748 . The epitope has these synonyms: (11Z,14Z)-N-[(2S,3S,4R)-1-(alpha-D-galactopyranosyloxy)-3,4-dihydroxyoctadecan-2-yl]icosa-11,14-dienamide, alpha-GalCer (C20:2), Galalpha-Cer(t18:0/20:2). This epitope has been studied for immune reactivity in 6 publication(s), tested in 32 T cell assays, 5 B cell assays, 3 MHC ligand assays and has 3D structure(s) 3UBX and 3ARF .

EPITOPE SUMMARY

1-O-(alpha-D-galactopyranosyl)-N-icosa-11,14-dienoylphytosphingosine (epitope ID

) has this structure:

. The epitope has these synonyms: (11Z,14Z)-N-[(2S,3S,4R)-1-(alpha-D-galactopyranosyloxy)-3,4-dihydroxyoctadecan-2-yl]icosa-11,14-dienamide, alpha-GalCer (C20:2), Galalpha-Cer(t18:0/20:2). This epitope has been studied for immune reactivity in

publication(s), tested in

T cell assays,

B cell assays,

MHC ligand assays and has 3D structure(s)

3UBX

and

3ARF

CURATED EXPERIMENTAL DATA
MHC Ligand Assay(s) 3
MHC molecule	Positive / All
mouse CD1d	2 / 2
chicken CD1-1	1 / 1

B Cell Assay(s) 5
Assay Type	Positive / All
3D structure	1 / 1
dissociation constant KD	1 / 1
off rate	1 / 1
on rate	1 / 1
qualitative binding	1 / 1

T Cell Assay(s) 32
Assay Type	Positive / All
IFNg release	7 / 7
IL-4 release	7 / 7
IL-2 release	5 / 5
qualitative binding	4 / 4
IL-13 release	3 / 3
proliferation	2 / 2
3D structure	1 / 1
dissociation constant KD	1 / 1
IL-17 release	1 / 1
TNFa release	1 / 1

EXTERNAL RESOURCES
Resource	Link
PubChem	11707590
GlyTouCan	G09546QO