EPITOPE SUMMARY
1-O-(4-deoxy-alpha-D-xylo-hexopyranosyl)-N-hexacosanoylsphinganine (epitope ID
164049
) has this structure:
CHEBI:63003
. The epitope has these synonyms: N-{(2S,3R)-1-[(4-deoxy-alpha-D-xylo-hexopyranosyl)oxy]-3-hydroxyoctadecan-2-yl}hexacosanamide, (2S,3R)-1-(4''-deoxy-alpha-D-galactopyranosyl)-2-hexacosanoylaminooctadecane-3-ol, 1-O-(4-deoxy-alpha-D-galactopyranosyl)-N-hexacosanoylsphinganine, 4',4''-deoxy-alpha-GalCer, 4-deoxy-Galalpha-Cer(d18:0/26:0), N-{(2S,3R)-1-[(4-deoxy-alpha-D-galactopyranosyl)oxy]-3-hydroxyoctadecan-2-yl}hexacosanamide. This epitope has been studied for immune reactivity in
6
publication(s), tested in
31
T cell assays,
2
B cell assays,
2
MHC ligand assays and has 3D structure(s)
3VWK
and
3ARE
.
CURATED EXPERIMENTAL DATA
MHC Ligand Assay(s)
2
MHC moleculePositive / All
human CD1d
1
/
1
mouse CD1d
1
/
1
B Cell Assay(s)
2
Assay TypePositive / All
decreased disease
0
/
2
T Cell Assay(s)
31
Assay TypePositive / All
qualitative binding
11
/
11
dissociation constant KD
7
/
7
on rate
3
/
3
3D structure
2
/
2
IL-2 release
2
/
2
IFNg release
1
/
1
IL-13 release
1
/
1
IL-17 release
1
/
1
IL-4 release
1
/
1
off rate
1
/
1
proliferation
1
/
1
EXTERNAL RESOURCES
ResourceLink
PubChem
45269857
GlyTouCan
G15807WA