reduced 6-(hydroxymethyl)-8-(1-D-ribityl)lumazine epitope

EPITOPE SUMMARY
reduced 6-(hydroxymethyl)-8-(1-D-ribityl)lumazine (epitope ID 178097 ) has this structure: CHEBI:70986 . The epitope has these synonyms: 1-deoxy-1-[6-(hydroxymethyl)-2,4-dioxo-3,4,6,7-tetrahydropteridin-8(2H)-yl]-D-ribitol, reduced 6-(hydroxymethyl)-8-D-ribityllumazine, rRL-6-CH2OH. This epitope has been studied for immune reactivity in 5 publication(s), tested in 28 T cell assays and 2 MHC ligand assays.

EPITOPE SUMMARY

reduced 6-(hydroxymethyl)-8-(1-D-ribityl)lumazine (epitope ID

) has this structure:

. The epitope has these synonyms: 1-deoxy-1-[6-(hydroxymethyl)-2,4-dioxo-3,4,6,7-tetrahydropteridin-8(2H)-yl]-D-ribitol, reduced 6-(hydroxymethyl)-8-D-ribityllumazine, rRL-6-CH2OH. This epitope has been studied for immune reactivity in

publication(s), tested in

T cell assays and

MHC ligand assays.

CURATED EXPERIMENTAL DATA
MHC Ligand Assay(s) 2
MHC molecule	Positive / All
human MR1	1 / 1
human MR1 K43A mutant	1 / 1

T Cell Assay(s) 28
Assay Type	Positive / All
activation	11 / 12
qualitative binding	5 / 5
IFNg release	3 / 3
TNF release	3 / 3
dissociation constant KD	2 / 2
IL-2 release	2 / 2
IL-17 release	0 / 1

EXTERNAL RESOURCES
Resource	Link
PubChem	70679253
GlyTouCan	G26534RZ