EPITOPE SUMMARY
1-O-{6-deoxy-6-[N'-(1-naphthyl)ureido]-alpha-D-galactopyranosyl}-N-hexacosanoylphytosphingosine (epitope ID
187236
) has this structure:
CHEBI:73554
. The epitope has these synonyms: N-[(2S,3S,4R)-1-({6-deoxy-6-[(naphthalen-1-ylcarbamoyl)amino]-alpha-D-galactopyranosyl}oxy)-3,4-dihydroxyoctadecan-2-yl]hexacosanamide, 1-O-(6-naphthoureido-6-deoxy-alpha-D-galactopyranosyl)-2-hexacosylamino-1,3,4-octadecanetriol, 1-O-{6-deoxy-6-[3-(1-naphthyl)ureido]-alpha-D-galactopyranosyl}-N-hexacosanoylphytosphingosine, NU-alpha-GalCer, NU-α-GalCer. This epitope has been studied for immune reactivity in
4
publication(s), tested in
18
T cell assays,
3
B cell assays,
3
MHC ligand assays and has 3D structure(s)
3QUZ
.
CURATED EXPERIMENTAL DATA
MHC Ligand Assay(s)
3
MHC moleculePositive / All
mouse CD1d
3
/
3
B Cell Assay(s)
3
Assay TypePositive / All
dissociation constant KD
1
/
1
off rate
1
/
1
on rate
1
/
1
T Cell Assay(s)
18
Assay TypePositive / All
proliferation
3
/
3
IFNg release
2
/
2
IL-2 release
2
/
2
IL-4 release
2
/
2
tumor burden after challenge
2
/
2
3D structure
1
/
1
activation
1
/
1
dissociation constant KD
1
/
1
off rate
1
/
1
on rate
1
/
1
qualitative binding
1
/
1
IL-10 release
0
/
1
EXTERNAL RESOURCES
ResourceLink
PubChem
25228911
GlyTouCan
G67550HR