EPITOPE SUMMARY
N-hexacosanoylisoglobotriaosyl ceramide (epitope ID
191036
) has this structure:
CHEBI:73269
. The epitope has these synonyms: N-[(2S,3R,4E)-1-{[alpha-D-galactopyranosyl-(1->3)-beta-D-galactopyranosyl-(1->4)-beta-D-glucopyranosyl]oxy}-3-hydroxyoctadec-4-en-2-yl]hexacosanamide, alpha-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-N-(hexacosanoyl)sphingosine, iGb3, isoglobotrihexosylceramide, iGb3 . This epitope has been studied for immune reactivity in
5
publication(s), tested in
22
T cell assays,
2
MHC ligand assays and has 3D structure(s)
3RZC
and
3SCM
.
CURATED EXPERIMENTAL DATA
MHC Ligand Assay(s)
2
MHC moleculePositive / All
mouse CD1d
2
/
2
T Cell Assay(s)
22
Assay TypePositive / All
dissociation constant KD
4
/
4
off rate
3
/
3
on rate
3
/
3
3D structure
2
/
2
IL-2 release
2
/
2
IFNg release
1
/
2
activation
1
/
1
IL-13 release
1
/
1
IL-17A release
1
/
1
IL-4 release
1
/
1
proliferation
1
/
1
qualitative binding
1
/
1
EXTERNAL RESOURCES
ResourceLink
PubChem
5497158
GlyTouCan
G78074HX