1-O-[6-O-(4-pyridylcarbamoyl)-alpha-D-galactopyranosyl]-N-hexacosanoylphytosphingosine epitope

EPITOPE SUMMARY
1-O-[6-O-(4-pyridylcarbamoyl)-alpha-D-galactopyranosyl]-N-hexacosanoylphytosphingosine (epitope ID 194670 ) has this structure: CHEBI:76100 . The epitope has these synonyms: N-{(2S,3S,4R)-3,4-dihydroxy-1-[6-O-(pyridin-4-ylcarbamoyl)-alpha-D-galactopyranosyloxy]octadecan-2-yl}hexacosanamide, alpha-GalCer-6"-(4-pyridyl)carbamate, alpha-GalCer-6"-(pyridin-4-yl)carbamate, PyrC-alpha-GalCer. This epitope has been studied for immune reactivity in 1 publication(s), tested in 10 T cell assays, 2 MHC ligand assays and has 3D structure(s) 4IRS .

EPITOPE SUMMARY

1-O-[6-O-(4-pyridylcarbamoyl)-alpha-D-galactopyranosyl]-N-hexacosanoylphytosphingosine (epitope ID

194670

) has this structure:

. The epitope has these synonyms: N-{(2S,3S,4R)-3,4-dihydroxy-1-[6-O-(pyridin-4-ylcarbamoyl)-alpha-D-galactopyranosyloxy]octadecan-2-yl}hexacosanamide, alpha-GalCer-6"-(4-pyridyl)carbamate, alpha-GalCer-6"-(pyridin-4-yl)carbamate, PyrC-alpha-GalCer. This epitope has been studied for immune reactivity in

publication(s), tested in

T cell assays,

MHC ligand assays and has 3D structure(s)

4IRS

CURATED EXPERIMENTAL DATA
MHC Ligand Assay(s) 2
MHC molecule	Positive / All
mouse CD1d	2 / 2

T Cell Assay(s) 10
Assay Type	Positive / All
3D structure	1 / 1
dissociation constant KD	1 / 1
IFNg release	1 / 1
IL-12 release	1 / 1
IL-13 release	1 / 1
IL-2 release	1 / 1
IL-4 release	1 / 1
off rate	1 / 1
on rate	1 / 1
tumor burden after challenge	1 / 1

EXTERNAL RESOURCES
Resource	Link
PubChem	71677796
GlyTouCan	G66334SN