GM3 lactam epitope - Immune Epitope Database (IEDB)

EPITOPE SUMMARY
GM3 lactam (epitope ID 2144557 ) has this structure: CHEBI:63532 . The epitope has these synonyms: N-{(2S,3R,4E)-1-[(4-O-{(2S,4S,4a'R,5R,5'S,6R,7'R,8'R,8a'R)-5-acetamido-4,8'-dihydroxy-7'-(hydroxymethyl)-3'-oxo-6-[(1R,2R)-1,2,3-trihydroxypropyl]decahydro-5'H-spiro[pyran-2,2'-pyrano[4,3-b][1,4]oxazin]-5'-yl}-beta-D-glucopyranosyl)oxy]-3-hydroxyoctadec-4-en-2-yl}octadecanamide, (2S,3R,4E)-3-hydroxy-2-(octadecanamide)octadec-4-enyl 4-O-[2-amino-2-deoxy-3-O-(5-acetamido-3,5-dideoxy-D-glycero-alpha-D-galacto-2-nonulopyranosyloyl-1''[*]2'-lactam)-beta-D-galactopyranosyl]-beta-D-glucopyranoside, GM3-lactam ceramide. This epitope has been studied for immune reactivity in 1 publication(s), tested in 1 T cell assay and 1 MHC ligand assay.

EPITOPE SUMMARY

GM3 lactam (epitope ID

) has this structure:

. The epitope has these synonyms: N-{(2S,3R,4E)-1-[(4-O-{(2S,4S,4a'R,5R,5'S,6R,7'R,8'R,8a'R)-5-acetamido-4,8'-dihydroxy-7'-(hydroxymethyl)-3'-oxo-6-[(1R,2R)-1,2,3-trihydroxypropyl]decahydro-5'H-spiro[pyran-2,2'-pyrano[4,3-b][1,4]oxazin]-5'-yl}-beta-D-glucopyranosyl)oxy]-3-hydroxyoctadec-4-en-2-yl}octadecanamide, (2S,3R,4E)-3-hydroxy-2-(octadecanamide)octadec-4-enyl 4-O-[2-amino-2-deoxy-3-O-(5-acetamido-3,5-dideoxy-D-glycero-alpha-D-galacto-2-nonulopyranosyloyl-1''[*]2'-lactam)-beta-D-galactopyranosyl]-beta-D-glucopyranoside, GM3-lactam ceramide. This epitope has been studied for immune reactivity in

publication(s), tested in

T cell assay and

MHC ligand assay.

CURATED EXPERIMENTAL DATA
MHC Ligand Assay(s) 1
MHC molecule	Positive / All
H2-Kb	1 / 1

T Cell Assay(s) 1
Assay Type	Positive / All
cytotoxicity	1 / 1

EXTERNAL RESOURCES
Resource	Link
PubChem	56927883
GlyTouCan	G43199IX