1-O-(alpha-D-galactosyl)-N-[(15Z)-tetracos-15-enoyl]phytosphingosine epitope

EPITOPE SUMMARY
1-O-(alpha-D-galactosyl)-N-[(15Z)-tetracos-15-enoyl]phytosphingosine (epitope ID 233318 ) has this structure: CHEBI:83272 . The epitope has these synonyms: (15Z)-N-[(2S,3S,4R)-1-(alpha-D-galactopyranosyloxy)-3,4-dihydroxyoctadecan-2-yl]tetracos-15-enamide, alphaGalCer (C24:1), PBS-44. This epitope has been studied for immune reactivity in 5 publication(s), tested in 22 T cell assays, 3 MHC ligand assays and has 3D structure(s) 4WW2 , 4WO4 and 4WWK .

EPITOPE SUMMARY

1-O-(alpha-D-galactosyl)-N-[(15Z)-tetracos-15-enoyl]phytosphingosine (epitope ID

) has this structure:

. The epitope has these synonyms: (15Z)-N-[(2S,3S,4R)-1-(alpha-D-galactopyranosyloxy)-3,4-dihydroxyoctadecan-2-yl]tetracos-15-enamide, alphaGalCer (C24:1), PBS-44. This epitope has been studied for immune reactivity in

publication(s), tested in

T cell assays,

MHC ligand assays and has 3D structure(s)

4WW2

4WO4

and

4WWK

CURATED EXPERIMENTAL DATA
MHC Ligand Assay(s) 3
MHC molecule	Positive / All
human CD1d	3 / 3

T Cell Assay(s) 22
Assay Type	Positive / All
3D structure	3 / 3
cytotoxicity	3 / 3
IFNg release	2 / 2
IL-4 release	2 / 2
qualitative binding	2 / 2
CCL3/MIP-1a release	1 / 1
GM-CSF release	1 / 1
IL-10 release	1 / 1
IL-13 release	1 / 1
IL-17A release	1 / 1
IL-2 release	1 / 1
TNF release	1 / 1
CCL2/MCP-1 release	0 / 1
IL-12 release	0 / 1
IL-6 release	0 / 1

EXTERNAL RESOURCES
Resource	Link
PubChem	71737844
GlyTouCan	G09546QO