EPITOPE SUMMARY
N(4)-{alpha-D-Manp-(1->2)-alpha-D-Manp-(1->2)-alpha-D-Manp-(1->3)-[alpha-D-Manp-(1->3)-[alpha-D-Manp-(1->2)-alpha-D-Manp-(1->6)]-alpha-D-Manp-(1->6)]-beta-D-Manp-(1->4)-beta-D-GlcpNAc-(1->4)-beta-D-GlcpNAc}-Asn residue (epitope ID
233377
) has this structure:
CHEBI:60628
studied as part of Envelope glycoprotein gp160 (UniProt:P04578) from Human immunodeficiency virus 1 (human immunodeficiency virus 1 HIV-1). The epitope has these synonyms: N(4)-{alpha-D-mannopyranosyl-(1->2)-alpha-D-mannopyranosyl-(1->2)-alpha-D-mannopyranosyl-(1->3)-[alpha-D-mannopyranosyl-(1->3)-[alpha-D-mannopyranosyl-(1->2)-alpha-D-mannopyranosyl-(1->6)]-alpha-D-mannopyranosyl-(1->6)]-beta-D-mannopyranosyl-(1->4)-2-acetamido-2-deoxy-beta-D-glucopyranosyl-(1->4)-2-acetamido--2-deoxy-beta-D-glucopyranosyl}-L-asparagine residue, (GlcNAc)2 (Man)8 (Asn)1, Man8GlcNAc2-Asn, N(4)-{alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-Asn residue, N(4)-{alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->6)]-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc}-L-Asn residue. This epitope has been studied for immune reactivity in
1
publication(s), tested in
4
B cell assays and has 3D structure(s)
4R2G
.
CURATED EXPERIMENTAL DATA
B Cell Assay(s)
4
Assay TypePositive / All
3D structure
2
/
2
dissociation constant KD
1
/
1
neutralization
1
/
1