EPITOPE SUMMARY
ITDQVPFSV is a linear peptidic epitope (epitope ID ) studied as part of Melanocyte protein PMEL (UniProt:P40967) from Homo sapiens (human), Melanocyte protein PMEL (UniProt:Q06154) from Bos taurus (bovine) and Melanocyte protein PMEL (UniProt:Q60696) from Mus musculus (mouse). This epitope has been studied for immune reactivity in publication(s), tested in T cell assays, MHC ligand assays and has 3D structure(s) , and .
CURATED EXPERIMENTAL DATA
MHC Ligand Assay(s)
MHC moleculePositive / All
HLA-A*02:01
HLA class I
HLA-A*01:01
HLA-A2
HLA-C*05:01
HLA-C*03:03
T Cell Assay(s)
Assay TypePositive / All
IFNg release
IL-2 release
qualitative binding
dissociation constant KD
activation
cytotoxicity
IL-17A release
degranulation
3D structure
GM-CSF release
IL-10 release
IL-6 release
TNFa release
tumor burden after challenge after adoptive transfer
binding constant
EXTERNAL RESOURCES
ResourceLink