EPITOPE SUMMARY
EAAGIGILTV is a linear peptidic epitope (epitope ID
10987
) studied as part of Melanoma antigen recognized by T-cells 1 (UniProt:Q16655) from Homo sapiens (human). The epitope is an analog of: EAAGIGILTV from Homo sapiens (human) melanoma antigen recognized by T-cells 1. The epitope is an analog of: EAAGIGILTV from Homo sapiens (human) Melanoma antigen recognized by T-cells 1. This epitope has been studied for immune reactivity in
53
publication(s), tested in
238
T cell assays,
4
B cell assays,
22
MHC ligand assays and has 3D structure(s)
6TMO
,
7Q9B
,
4QOK
and
2GT9
.
CURATED EXPERIMENTAL DATA
MHC Ligand Assay(s)
22
MHC moleculePositive / All
HLA-A*02:01
21
/
22
B Cell Assay(s)
4
Assay TypePositive / All
qualitative binding
4
/
4
T Cell Assay(s)
238
Assay TypePositive / All
qualitative binding
63
/
64
TNFa release
31
/
31
cytotoxicity
30
/
31
IFNg release
20
/
22
CCL4/MIP-1b release
20
/
20
off rate
17
/
17
degranulation
10
/
11
activation
8
/
8
dissociation constant KD
8
/
8
proliferation
8
/
8
IL-2 release
4
/
4
3D structure
3
/
3
granzyme B release
2
/
2
T cell- APC binding
2
/
2
tumor burden after challenge after adoptive transfer
2
/
2
decreased disease
1
/
1
IL-13 release
1
/
1
IL-4 release
1
/
1
protection from tumor challenge after adoptive transfer
1
/
1
survival after tumor challenge after adoptive transfer
1
/
1
EXTERNAL RESOURCES
ResourceLink
IEDB-AR: MHC-I Processing
Predict MHC class I processing
IEDB-AR: MHC-I
Predict MHC class I binding affinity
IEDB-AR: B cell scales
Predict B cell epitopes