EPITOPE SUMMARY
EISTNIRQAGVQYSR is a linear peptidic epitope (epitope ID
12584
) studied as part of ESAT-6-like protein EsxB (UniProt:P9WNK5) from Mycobacterium tuberculosis. This epitope has been studied for immune reactivity in
11
publication(s), tested in
35
T cell assays,
5
B cell assays and
26
MHC ligand assays.
CURATED EXPERIMENTAL DATA
MHC Ligand Assay(s)
26
MHC moleculePositive / All
HLA-DPA1*02:01/DPB1*01:01
1
/
1
HLA-DQA1*01:01/DQB1*05:01
1
/
1
HLA-DQA1*01:02/DQB1*06:02
1
/
1
HLA-DQA1*03:01/DQB1*03:02
1
/
1
HLA-DQA1*05:01/DQB1*02:01
1
/
1
HLA-DQA1*05:01/DQB1*03:01
1
/
1
HLA-DRB1*01:01
1
/
1
HLA-DRB1*03:01
1
/
1
HLA-DRB1*04:01
1
/
1
HLA-DRB1*04:04
1
/
1
HLA-DRB1*04:05
1
/
1
HLA-DRB1*08:02
1
/
1
HLA-DRB1*09:01
1
/
1
HLA-DRB1*11:01
1
/
1
HLA-DRB1*12:01
1
/
1
HLA-DRB1*13:02
1
/
1
HLA-DRB1*15:01
1
/
1
HLA-DRB3*02:02
1
/
1
HLA-DRB4*01:01
1
/
1
HLA-DRB5*01:01
1
/
1
HLA-DPA1*01:03/DPB1*02:01
0
/
1
HLA-DPA1*01:03/DPB1*04:01
0
/
1
HLA-DPA1*02:01/DPB1*05:01
0
/
1
HLA-DPA1*03:01/DPB1*04:02
0
/
1
HLA-DRB1*07:01
0
/
1
HLA-DRB3*01:01
0
/
1
B Cell Assay(s)
5
Assay TypePositive / All
qualitative binding
2
/
4
pathogen burden after challenge
0
/
1
T Cell Assay(s)
35
Assay TypePositive / All
IFNg release
26
/
26
IL-2 release
2
/
2
TNFa release
2
/
2
proliferation
1
/
1
qualitative binding
1
/
1
type IV hypersensitivity (DTH)
1
/
1
IL-4 release
0
/
1
pathogen burden after challenge
0
/
1
EXTERNAL RESOURCES
ResourceLink
IEDB-AR: MHC-I Processing
Predict MHC class I processing
IEDB-AR: MHC-I
Predict MHC class I binding affinity
IEDB-AR: MHC-II
Predict MHC class II binding affinity
IEDB-AR: B cell scales
Predict B cell epitopes