| EPITOPE SUMMARY | |
|---|---|
| SIINFEKL is a linear peptidic epitope (epitope ID ) studied as part of Gal d 2 (UniProt:P01012) from Gallus gallus (chicken). This epitope has been studied for immune reactivity in publication(s), tested in T cell assays, B cell assays, MHC ligand assays and has 3D structure(s) , , , , , , , , , , , and . | |
| CURATED EXPERIMENTAL DATA | |
|---|---|
MHC Ligand Assay(s) | |
| MHC molecule | Positive / All |
| H2-Kb | / |
| H2-Db | / |
| H2-Kb Y22F, M23I, E24S, D30N mutant | / |
| H2-Kb Y84C mutant | / |
| H2-Kb E152A, R155Y, L156Y mutant | / |
| H2-Kb E63A mutant | / |
| H2-Kb K66A mutant | / |
| H2-Kb W167A mutant | / |
| H2-Kb Y84A mutant | / |
| H2-Dd | / |
| HLA-A*02:01 | / |
| H2-Ld | / |
| H2-IAb | / |
| H2-Kd | / |
| H2-Q1 | / |
| HLA class I | / |
| HLA-A2 | / |
| Mamu-A1*002:01 | / |
B Cell Assay(s) | |
| Assay Type | Positive / All |
| association constant KA | / |
| off rate | / |
| on rate | / |
| qualitative binding | / |
T Cell Assay(s) | |
| Assay Type | Positive / All |
| IFNg release | / |
| qualitative binding | / |
| cytotoxicity | / |
| proliferation | / |
| IL-2 release | / |
| activation | / |
| proliferation after adoptive transfer | / |
| TNFa release | / |
| protection from tumor challenge | / |
| association constant KA | / |
| degranulation | / |
| granzyme B release | / |
| off rate | / |
| on rate | / |
| cytotoxicity after adoptive transfer | / |
| TNF release | / |
| tumor burden after challenge | / |
| decreased disease | / |
| survival from tumor challenge | / |
| pathogen burden after challenge | / |
| disease exacerbation after adoptive transfer | / |
| IL-4 release | / |
| IL-6 release | / |
| pathogen burden after challenge after adoptive transfer | / |
| survival after pathogen challenge after adoptive transfer | / |
| T cell- APC binding | / |
| tolerance after adoptive transfer | / |
| disease exacerbation | / |
| EXTERNAL RESOURCES | |
|---|---|
| Resource | Link |