EPITOPE SUMMARY
YLEPGPVTA is a linear peptidic epitope (epitope ID
74638
) studied as part of Melanocyte protein PMEL (UniProt:P40967) from Homo sapiens (human). This epitope has been studied for immune reactivity in
37
publication(s), tested in
62
T cell assays,
15
MHC ligand assays and has 3D structure(s)
5EU3
.
CURATED EXPERIMENTAL DATA
MHC Ligand Assay(s)
15
MHC moleculePositive / All
HLA-A*02:01
14
/
14
HLA class I
1
/
1
T Cell Assay(s)
62
Assay TypePositive / All
IFNg release
13
/
20
qualitative binding
9
/
9
cytotoxicity
8
/
8
activation
6
/
6
IL-2 release
3
/
3
TNF release
3
/
3
CCL4/MIP-1b release
2
/
2
dissociation constant KD
2
/
2
IL-10 release
2
/
2
proliferation
2
/
2
TNFa release
2
/
2
degranulation
1
/
1
survival after tumor challenge after adoptive transfer
1
/
1
tumor burden after challenge after adoptive transfer
1
/
1
EXTERNAL RESOURCES
ResourceLink
IEDB-AR: MHC-I Processing
Predict MHC class I processing
IEDB-AR: MHC-I
Predict MHC class I binding affinity
IEDB-AR: B cell scales
Predict B cell epitopes