Welcome
The Immune Epitope Database (IEDB) is a freely available resource funded by NIAID. It catalogs experimental data on antibody and T cell epitopes studied in humans and other animal species in the context of infectious disease, allergy, autoimmunity and transplantation. The IEDB also hosts epitope prediction and analysis tools, and has a companion site, CEDAR (funded by NCI), which houses cancer epitopes.
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Epitope
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Any
Linear peptide
Discontinuous
Non-peptidic
Assay
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T Cell
B Cell
MHC Ligand
Outcome:
Positive
Negative
Epitope Source
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Organism
Antigen
MHC Restriction
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Any
Class I
Class II
Non-classical
Host
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Any
Human
Mouse
Non-human primate
Disease
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Any
Infectious
Allergic
Autoimmune
T Cell Epitope Prediction
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Scan an antigen sequence for amino acid patterns indicative of:
MHC I Binding
MHC II Binding
MHC I Processing (Proteasome,TAP)
MHC I Immunogenicity
B Cell Epitope Prediction
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Predict linear B cell epitopes using:
Antigen Sequence Properties
Predict discontinuous B cell epitopes using antigen structure via:
Discotope
ElliPro
Epitope Analysis Tools
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Analyze epitope sets of:
Population Coverage
Conservation Across Antigens
Clusters with Similar Sequences