T cell receptor (receptor group ID
125
)
Alpha beta TCR with alpha chain CDR3 of ATDTTSGTYKYI and beta chain CDR3 of SARDLTSGANNEQF was reported in Homo sapiens (human). This TCR has accessions for alpha chain
2WBJ_C
,
1YMM_D
and beta chain
2WBJ_D
,
1YMM_E
and was shown in 3D Structures
2WBJ
and
1YMM
.
alphabetaEpitopes (# assays)
Gene usageCDR sequencesGene usageCDR sequences
V:TRAV17*01
D:
J:TRAJ40*01		CDR1:TSINN
CDR2:IRSNERE
CDR3:ATDTTSGTYKYI		V:TRBV20-1*01
D:
J:TRBJ2-1*01		CDR1:DFQATT
CDR2:SNEGSKA
CDR3:SARDLTSGANNEQF		ENPVVHFFKNIVTPR (
2
), ALAVLHFYPDKGAKN (
1
), DFARVHFISALHGSG (
5
), QRCRVHFLRNVLAQV (
2
), QRCRVHFMRNLYTAV (
1
)
V Domain: QQGEEDPQALSIQEGENATMNCSYKTSINN...
V Domain: AVVSQHPSWVISKSGTSVKIECRSLDFQAT...
V:TRAV17*01
D:
J:TRAJ40*01		CDR1:TSINN
CDR2:IRSNERE
CDR3:ATDTTSGTYKYI		V:TRBV20-1*01
D:
J:TRBJ2-1*01		CDR1:DFQATT
CDR2:SNEGSKA
CDR3:SARDLTSGANNEQF		AHPADPGSRPHLIRLFSRDA (
4
), EKPKFEAYKAAAAPA (
1
), EKPKVEAYKAAAAPA (
1
), EKPKYEAYKAAAAPA (
1
), ENPVVHFFKNIVTPR (
34
), ITREEKPAVTAAPKK (
4
), PGSRPHLIRLFSRDA (
4
), TLDISNNRLESLPAH (
3
), TTSEDNEVFGEADANQNNGTSS (
4
), ALAVLHFYPDKGAKN (
5
), DFARVHFISALHGSG (
8
), QRCRVHFLRNVLAQV (
6
), QRCRVHFMRNLYTAV (
5
), VLARLHFYRNDVHKE (
5
), ATDTTSGTYKYIFGTGTRLKVLA (
2
), SARDLTSGANNEQFFGPGTRLTVL (
2
)
V Domain: QQGEEDPQALSIQEGENATMNCSYKTSINN...
V Domain: AVVSQHPSWVISKSGTSVKIECRSLDFQAT...
V:TRAV17*01
D:
J:TRAJ40*01		CDR1:TSINN
CDR2:IRSNERE
CDR3:ATDTTSGTYKYI		V:TRBV20-1*01
D:
J:TRBJ2-1*01		CDR1:DFQATT
CDR2:SNEGSKA
CDR3:SARDLTSGANNEQF		ENPVVHFFKNIVTPR (
1
)
V Domain: V Domain:
Epitope summary
This TCR was studied for the following epitopes ENPVVHFFKNIVTPR studied as part of Myelin basic protein (UniProt:P02687) from Bos taurus (bovine) (epitope ID
13572
,
7
publications,
36
assays), ALAVLHFYPDKGAKN studied as part of N-acetylmuramoyl-L-alanine amidase CwlH (UniProt:P54450) from Bacillus subtilis (epitope ID
115681
,
2
publications,
6
assays), DFARVHFISALHGSG studied as part of GTPase Der (UniProt:P0A6P5) from Escherichia coli (epitope ID
115706
,
2
publications,
10
assays), QRCRVHFLRNVLAQV studied as part of Mutator family transposase (UniProt:Q741E1) from Mycobacterium avium (epitope ID
115926
,
2
publications,
7
assays), QRCRVHFMRNLYTAV studied as part of Mutator family transposase (UniProt:I6XH73) from Mycobacterium tuberculosis (epitope ID
115927
,
2
publications,
6
assays), AHPADPGSRPHLIRLFSRDA studied as part of Myelin basic protein (UniProt:P02686) from Homo sapiens (human) (epitope ID
1806
,
1
publication,
4
assays), EKPKFEAYKAAAAPA (epitope ID
12838
,
1
publication,
1
assay), EKPKVEAYKAAAAPA (epitope ID
12841
,
1
publication,
1
assay), EKPKYEAYKAAAAPA (epitope ID
12842
,
1
publication,
1
assay), ITREEKPAVTAAPKK studied as part of Alpha-crystallin B chain (UniProt:P02511) from Homo sapiens (human) (epitope ID
29066
,
1
publication,
4
assays), PGSRPHLIRLFSRDA studied as part of Myelin basic protein (UniProt:P02686) from Homo sapiens (human) (epitope ID
47754
,
1
publication,
4
assays), TLDISNNRLESLPAH studied as part of Oligodendrocyte-myelin glycoprotein (UniProt:P23515) from Homo sapiens (human) (epitope ID
64754
,
1
publication,
3
assays), TTSEDNEVFGEADANQNNGTSS studied as part of Myelin basic protein (UniProt:P02686) from Homo sapiens (human) (epitope ID
66814
,
1
publication,
4
assays), VLARLHFYRNDVHKE studied as part of ABC transporter, ATP-binding protein (UniProt:Q2G091) from Staphylococcus aureus (epitope ID
116015
,
1
publication,
5
assays), ATDTTSGTYKYIFGTGTRLKVLA studied as part of T cell receptor alpha chain MC.7.G5 (UniProt:P0DTU3) from Homo sapiens (human) (epitope ID
133523
,
1
publication,
2
assays) and SARDLTSGANNEQFFGPGTRLTVL studied as part of T cell receptor beta chain MC.7.G5 (UniProt:P0DTU4) from Homo sapiens (human) (epitope ID
133689
,
1
publication,
2
assays).